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FDA Approves Investigational Trials Assessing Cannabidiol For Pediatric Epilepsy

Washington, DC: The US Food and Drug Administration has approved two clinical trials to assess the efficacy of cannabidiol (CBD), a nonpsychoactive plant cannabinoid, in the treatment of intractable pediatric epilepsy. The two approved trials will take place at New York Medical School and at the University of California at San Francisco, according to an online report in the journal O'Shaughnessy's. The cannabidiol formulations in the trials will be provided by British biotechnology firm GW Pharmaceuticals, which produces organic cannabinoid extract medicines, including Sativex.

Study shows non-hallucinogenic cannabinoids are effective anti-cancer drugs

New research has shown that the non-hallucinogenic components of cannabis could act as effective anti-cancer agents.

The anti-cancer properties of tetrahydrocannabinol (THC), the primary hallucinogenic component of cannabis, has been recognised for many years, but research into similar cannabis-derived compounds, known as cannabinoids, has been limited.

The study was carried out by a team at St George’s, University of London. It has been published in the journal Anticancer Research.

Study Finds Cannabis Protects Against Sepsis

According to a study published earlier this year by the National Institute of Health, activation of the body’s cannabinoid receptors – something which cannabis does naturally – can protect against sepsis, a serious inflammatory illness which is due to a severe reaction to bacteria or germs, which often proves fatal.

During the study, which used mice subjects, researchers found that activation of the cannabinoid receptor 2 (CB2R) can “significantly extend the survival rate and decrease serum proinflammatory cytokines” in those with sepsis.

Cannabis May Treat Celiac Disease, According to Recent Government-Published Study

A National Institute of Health study published earlier this year found that cannabis may treat celiac disease by activating the body’s natural cannabinoid receptors. Celiac disease is an autoimmune disorder of the small intestine which some people are genetically predisposed to.

The study, which was conducted by researchers at the Department of Biomedical Sciences at the University of Teramo in Italy, aimed to “investigate the expression of CBR [cannabinoid receptors] at transcriptional and translational levels in the duodenal mucosa of untreated celiac patients, celiac patients on a gluten-free diet for at least 12 months and control subjects. Also biopsies from treated celiac patients cultured ex vivo with peptic-tryptic digest of gliadin were investigated.”

Study Finds Cannabis-Infused Microparticles Effectively Inhibit Tumor Growth

A study published recently by the journal PLoS One, as well as the National Institute of Health, has found that cannabis-infused microparticles can be an effective anticancer agent.

For the study, researchers “analyzed CBD- and THC-loaded poly-ε-caprolactone microparticles as an alternative delivery system for long-term cannabinoid administration in a murine xenograft model of glioma [a type of tumor]”

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