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Study Finds Cannabis-Infused Microparticles Effectively Inhibit Tumor Growth

A study published recently by the journal PLoS One, as well as the National Institute of Health, has found that cannabis-infused microparticles can be an effective anticancer agent.

For the study, researchers “analyzed CBD- and THC-loaded poly-ε-caprolactone microparticles as an alternative delivery system for long-term cannabinoid administration in a murine xenograft model of glioma [a type of tumor]”

cannabis cannabinoids thc cbd cancer  tumorAccording to the study; “In vitro characterization of THC- and CBD-loaded microparticles showed that this method of microencapsulation facilitates a sustained release of the two cannabinoids for several days”, it continues; “Local administration of THC-, CBD- or a mixture of THC- and CBD-loaded microparticles every 5 days to mice bearing glioma xenografts reduced tumour growth with the same efficacy than a daily local administration of the equivalent amount of those cannabinoids in solution”, demonstrating that the microparticles may be more effective at combating tumors than standardized forms of administration (such as inhalation or ingestion).

Researchers found conclusive evidence that “cannabinoid-loaded microparticles enhanced apoptosis and decreased cell proliferation and angiogenesis in these tumours.”

They conclude: “Our findings support that THC- and CBD-loaded microparticles could be used as an alternative method of cannabinoid delivery in anticancer therapies.”

The study can be found in its entirety by clicking here.

Source: thejointblog.com

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